Selected Publications

Antibody Arrays

2017

Journals Array Platform
Amaya CN, Mitchell DC, Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth, BMC Cancer, 2017 Jul 14, 17(1):485. doi: 10.1186/s12885-017-3470-7 [PubMed] Phospho Explorer Array
Cai W, Chen G, PMP22 Regulates Self-Renewal and Chemoresistance of Gastric Cancer Cells, Mol Cancer Ther 2017; doi: 10.1158/1535-716 [PubMed] Explorer Antibody Array
Cook DP, Adam RJ, CF airway smooth muscle transcriptome reveals a role for PYK2. JCI Insight. 2017;2(17) [PubMed] Phospho Explorer Array
Feng Y, He F, The Role of GOLPH3L in the Prognosis and NACT response in Cervical Cancer, J Cancer 2017; 8(3):443-454 [jcancer.org] MAPK Phospho Array
Gao S, Li S, Inhibition of glycogen synthase kinase 3 beta (GSK3β) suppresses the progression of esophageal squamous cell carcinoma by modifying STAT3 activity, Mol Carcinog 2017;56(10):2301-2316" [PubMed] Cancer Signaling Phospho Array
Ge Z, Diao H,Connexin 43 mediates changes in protein phosphorylation in HK-2 cells during chronic cadmium exposure. Environ Toxicol Pharmacol. 2017 Jul;53:184-190 [PubMed] Phospho Explorer Array
Han KH, Kim AK, Protein profiling and angiogenic effect of hypoxia-cultured human umbilical cord blood-derived mesenchymal stem cells in hindlimb ischemia, Tissue Cell 2017,  pii: S0040-8166(16)30363-9 [PubMed] Phospho Explorer Array
Hillard T, Miklossy G, 15∝-methoxypuupehenol induces antitumor effects in vitro and in vivo against human glioblastoma and breast cancer models, Mol Cancer Ther 2017 Jan 9, doi: 10.1158/1535-7163 [PubMed] Phospho Explorer Array
Kawamura D, Takemoto Y, Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells, Onc Reports 2017; 38(5):3238-3244 [Abstract] Cancer Signaling Phospho Array
Klimushina MV, Gumanova NG, Direct labeling of serum proteins by fluorescent dye for antibody microarray, Biochem Biophys Res Commun 2017; 486(3):824-826 [PubMed] Signaling Explorer Antibody Array
Explorer Antibody Array
Koppenhagen P, Dickreuter E, Head and neck cancer cell radiosensitization upon dual targeting of c-Abl and beta1-integrin. Radiother Oncol. 2017 Jul;53:184-190 [PubMed] Phospho Explorer Array
Lee TG, Jeong EH, Fhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells, Oncotarget, 2017;8(19):31923-31937 [PubMed] Explorer Antibody Array
Ling Q, Xu X, The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma, Oncotarget 2017; 8(9):15159-15167 [PubMed] Signaling Explorer Array
Ling S, Xie H, Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1, J Hematol Oncol 2017; 10(1):59 [PubMed] Cancer Signaling Phospho Array
Luna-Vital D, Weiss M, Anthocyanins from Purple Corn Ameliorated TNF-α-Induced Inflammation and Insulin Resistance in 3T3-L1 Adipocytes via Activation of Insulin Signaling and Enhanced GLUT4 Translocation, Mol Nutr Food Res, 2017 July 31, doi: 10.1002/mnfr.201700362 [PubMed] Insulin Receptor Phospho Array
Mazer J, Rosado A, The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma, Oncotarget 2017; 8(4):6589-6607 [PMC] p53 Signaling Phospho Array
Oda K, Umemura M, Transient receptor potential cation 3 channel regulates melanoma proliferation and migration, J Physiol Sci. 2017; 67(4):497-505 [PubMed] Cancer Signaling Phospho Array
Rahal O, Wolfe A, Blocking IL4- and IL13-mediated phosphorylation of STAT6 (Tyr641) decreases M2 polarization of macrophages and protects against macrophage-mediated radioresistance of inflammatory breast cancer, JROBP (2018), doi: 10.1016/j.ijrobp.2017.11.043[JROBP] Kinase Antibody Array
Pan X, Jiang B, STC1 promotes cell apoptosis via NF-κB phospho-P65 Ser536 in cervical cancer cells, Oncotarget 2017; 8(28):46249-46261 [PubMed] NFkB Phospho Array
Park HL, Lee SM, IK acts as an immunoregulator of inflammatory arthritis by suppressing TH17 cell differentiation and macrophage activation, Sci Reports 7, 2017:40280 [nature.com] Phospho Explorer Array
Sakumoto M, Takahashi M, Establishment and proteomic characterization of NCC-LMS1-C1, a novel cell line of primary leiomyosarcoma of the bone, Japanese J Clin Oncol, 2017 Jul 13:1-8 [JJCO] Signaling Explorer Array
Saykally JN, Hatic H, Withania somnifera Extract Protects Model Neurons from In Vitro Traumatic Injury, Cell Transplant, 2017;26(7):1193-1201 [Sage Journals] Apoptosis Phospho Antibody Array
Schubert KM, Qiu J, The AMP-Related Kinase (AMPK) Induces Ca2+-Independent Dilation of Resistance Arteries by Interfering with Actin Filament Formation, Circulation Res, 2017 121:149-161[AHA Journals] Cytoskeleton Phospho Array
Shi F, Guo H, The PI3K inhibitor GDC-0941 enhances radiosensitization and reduces chemoresistance to temozolomide in GBM cell lines, Neuroscience 2017, 346:298-308 [PubMed] Phospho Explorer Array
Suh JS, Lee HJ, Control of cancer stem cell like population by intracellular target identification followed by the treatment with peptide-siRNA complex, Biochem & Biophys Res Commu, 2017 May 26, pii: S0006-291X(17)31048-3 [PubMed] Phospho Explorer Array
Tian X, Jin X, The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway, Mol Cancer 2017, 16:74 [PMC] Cell Cycle Array
Vehlow A, Klapproth E, Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by β1 integrin/JNK co-targeting. Oncotarget. 2017;8(30):49224-49237 [PubMed] Phospho Explorer Array
Wu Y, Su M, Abnormal expression of TGF-beta type II receptor isoforms contributes to acute myeloid leukemia, Oncotarget 2017, 8(6):10037-10049 [PubMed] TGF-beta Phospho Array
Yang EJ, Mahmood U, Alterations in protein phosphorylation in the amygdala of the 5XFamilial Alzheimer's disease animal model, J Pharmaco Sci, 2017;133(4):261-267[PubMed] Phospho Explorer Array
Yang Y, Lian S, Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion, PLoS One, 2017 Jan 9, http://dx.doi.org/10.1371/journal.pone.0169665 [PLOS] Phospho Explorer Array
Yim JH, Yun JM, Estimation of low-dose radiation-responsive proteins in the absence of genomic instability in normal human fibroblast cells, Int J Radiat Biol, 2017 Jul 6:1-29. doi: 10.1080/09553002.2017.1350302 [PubMed] Phospho Explorer Array
Wei X, Sun Y, Downregulation of Talin-1 expression associates with increased proliferation and migration of vascular smooth muscle cells in aortic dissection, BMC Cardiovasc Disord. 2017;17(1):162 [PubMed] Cell Cycle Array

2016

Journals Array Platform
Gao Y, Bai X, Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis, Nat Struct Mol Biol 2016 23(5):441-9 [PubMed] Phospho Explorer Array
Garnett D, Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer, J Cancer Res Clin Oncol 2016, 142:611–618 [Springer] Signaling Explorer Antibody Array
Gruosso T, Mieulet V, Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients, EMBO Mol Med 2016 Mar 22. pii: e201505891. doi: 10.15252/emmm.201505891 [PubMed] Cell Cycle Control Phospho Antibody Array
Gu C, Feng M, RalA, a GTPase targeted by miR‑181a, promotes transformation and progression by activating the Ras‑related signaling pathway in chronic myelogenous leukemia, Oncotarget, 2016 Mar 8. doi: 10.18632/oncotarget.7987 [PubMed] Cancer Signaling Phospho Antibody Array
Gupta S, Manubhai KP, An overview of innovations and industrial solutions Portein Microarray Technology, Proteomics, 2016 April 4, doi: 10.1002/pmic.201500429 [Wiley]
Huang M, Lou D, Pyrrolidine dithiocarbamate attenuates paraquat-induced acute pulmonary poisoning in vivo via transforming growth factor β1 and nuclear factor κB pathway interaction, Hum Exp Toxicol 2016 Feb 9, pii: 0960327116630351 [PubMed] Phospho Explorer Array
Hwang HJ, Jung SH, Identification of novel therapeutic targets in the secretome of ionizing radiation‑induced senescent tumor cells, Oncol Rep, 2016 35(2):841-850 [Oncology Reports] Cytokine Profiling Array
Jiang HL, Sun HF, SSBP1 Suppresses TGF-β-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling, Cancer Res 2016 76(4):952-64 [PubMed] Phospho Explorer Array
Kuang XY, Jiang HS, The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis, Cancer Lett 2016 377(1):87-96 [PubMed] Phospho Explorer Array
Park HJ, Oh JS, Proton Irradiation Sensitizes Radioresistant Non-small Cell Lung Cancer Cells by Modulating Epidermal Growth Factor Receptor-mediated DNA Repair, Anticancer Res, 2016 36(1):205-12 [PubMed] Signaling Explorer Array
Pulito C, Sacconi A, Antibody Array as a Tool for Screening of Natural Agents in Cancer Chemoprevention, Methods Mol Biol, 2016 1379:189-99 [PMC] Phospho Explorer Array
Shah A, Kannambath S, Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus During Macrophage Cell Death, Am J Respir Crit Care Med, 2016 May 10 [PubMed] Phospho Explorer Array
Tan X, Liu P, Phosphoproteome Analysis of Invasion and Metastasis-Related Factors in Pancreatic Cancer Cells, PLOS One, 2016 March 25, DOI: 10.1371/journal.pone.0152280 [PLOS One] Phospho Explorer Array
Xu J, Zhou L, The REGγ-proteasome forms a regulatory circuit with IκBε and NFκB in experimental colitis, Nat Commun, 2016 Feb 7:10761 [PMC] Phospho Explorer Array
Yang T, Yao H, Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis, Journal of Cancer 2016; 7(2): 192-199 [PDF] Explorer Antibody Array
Zhu Y, Dai B, Long non-coding RNA LOC572558 inhibits bladder cancer cell proliferation and tumor growth by regulating the AKT-MDM2-p53 signaling axis, Cancer Lett, 2016 Apr 26, doi:10.1016/j.canlet.2016.04.030 [PubMed] Cancer Signaling Phospho Antibody Array
Zhu R, Wang Q, pH sensitive nano layered double hydroxides reduce the hematotoxicity and enhance the anticancer efficacy of etoposide on non-small cell lung cancer, Acta Biomater, 2016 29:320-332 [PubMed] Cancer Signaling Phospho Antibody Array

 

Additional Publications

Scanner Calibration Slides

Lee JK., Heimer BW, Systematic study of fluorescein-functionalized macrophotoinitiators for colorimetric bioassays, Biomacromolecules 13.4 (2012): 1136-1143

Risinger A, Williams C: ScanArray Gx Plus/ProScanArray Competitive Performance Analysis Using a Commercial Test Slide, Application Note, PerkinElerm Life and Analytical Sciences, Shelton, CT, USA, www.perkinelmer.com.
“The Full Moon BioSystems All Purpose Scanner Evaluation Slide (Prod # AV05) was used to perform these experiments…”

Shi L, Tong W, et al.: Microarray Scanner Calibration Curves: Characteristics and Implications, BMC Bioinformatics 2005, 6(Suppl 2):S11.
“The microarray scanner calibration slide from Full Moon BioSystems Inc. (Sunnyvale, CA, USA) has been developed for performing quantitative evaluations microarray scanners in terms of dynamic range, limit of detection, uniformity of microarray scanners, channel-to-channel cross-talk, and laser stability.”

Wang L, Gaigalas A, et al.: Effect of Target and Probe Concentrations on Hybridization in DNA Microarrays, Microarray and Combinatorial Techniques: Design, Fabrication, and Analysis II. Edited by Nicolau, Dan V; Raghavachari, Ramesh. Proceeding of the SPIE, Vol. 5328, pp. 129-139 (2004).
“Scanner Calibration Slides (manufactured by Full Moon BioSystems) were used to concert the fluorescence signals into fluorophore per um2 in order eliminate possible variation from scanner.”

Zhang Y, Milam VT, et al.: Differential Adhesion of Microspheres Mediated by DNA Hybridization I: Experiment, Biophysical Journal, 90:4128-4136 (2006).
“The slides are then scanner with ScanArray 5000 (PerkinElmer Life and Analytical Sciences, Wellesley, MA) and the fluorescent intensity is compared with that of a calibration slide (Full Moon BioSystems, Sunnyvale, CA).”

Microarray Slides

Chen C, Korobkova E, et al.: A Proteome Chip Approach Reveals New DNA Damage Recognition Activities in Escherichia coli, Nature Methods, 5 (1), Jan. 2008.
“Different surface chemistries were tested, including the FullMoon, aldehyde-derivatized, hydrogel- and nitrocellulose-coated (FAST slides) surfaces. All of the tests produced satisfactory immobilization results, with the FullMoon surfaces performing the best.” ”
“To optimize the binding conditions, we carried out a series of pilot assays and determined that the FullMoon surface produced the best signal-to-noise ratio with a stringent high-salt wash.”

Covarrubia MY, Khan R, et al.: Chronic Alcohol Exposure Alters Transcription Broadly in a Key Integrative Brain Nucleus for Homeostasis: the nucleus tracus solitarius, Physiological Genomics 2005.
“cDNA were mixed with an equal volume of DMSO (10-70 ng/ul) and printed on FMB cDNA slides (Full Moon BioSystems, Sunnyvale, CA) using a MicroGrid II arrayer…”

Dhar MS, Yuan JS, et al.: A Type IV P-Type ATPase Affects Insulin-mediated Glucose Uptake in Adipose Tissue and Skeletal Muscle in Mice, Journal of Nutritional Biochemistry, 17 (12), 811-820 (2007).
“The mouse whole genome long-oligo set was printed on the PowerMatrix Slides (Full Moon BioSystems, Sunnyvale, CA, USA).”

Ding M, Gao Q, et al.: Construction and Validation of an Insecticide Resistence-Associated DNA Microarray, Journal Pesticide Science 2007, 32(1), 32-41
“…the diluted products were spotted onto FMB slides (Full Moon BioSystems) using a robotic spotting system (GeneMachine).”

Ellestad LE, Carre W, et al.: Gene Expression Profiling During Cellular Differentiation in the Embryonic Pituitary Gland Using cDNA Microarrays, Physical Genomics 2006, 25: 414-425.
“PCR products were rearrayed into 384-well plates in 50% DMSO and printed onto glass microscope slides (Full Moon BioSystems, Sunnyvale, CA) as high-density cDNA microarrays at Delaware Biotechnology Institute…”

Gardiner JM, Buell CR, Design, Production, and Utilization of Long Oligonucleotide Microarrays for Expression Analysis in Maize, Maydica 2005 50: 425-435.
“The long oligo microarrays were spotted on …specially coated PowerMatrix slides (Full Moon BioSystems, Sunnyvale, CA)…”

Gertych , Oh JH, 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models, BMC Pharmacology and Toxicology 2013, 14:11

Horiuchi KY, Wang Y, Microarray for the Functional Analysis of the Chemica-Kinase Interactome, Journal of Biomolecular Screening X(X); 2006.
“Protein slides to immobilize proteins were purchased from Full Moon BioSystems (Sunnyvale, CA).” … “Full Moon BioSystems Protein slides were found to bind up to 500 nM of MEK in the printing solution (compared to 300 nM on the epoxy slide).”

Huang R, Lin Y, Enhanced Protein Profiling Arrays with ELISA-Based Amplification for High-Throughput Molecular Changes of Tumor Patients’ Plasma, Clinical Cancer Research, 2004 10: 598-609.
“One of the advance technologies in protein arrays is the three-dimensional substrate chip. To test whether our system can also be sued to enhance detection sensitivity in three-dimensional substrate chips from Full Moon BioSystems (Sunnyvale, CA)…”

Olah J, Orosz F, et al.: Triosephosphate Isomerase Deficiency: Consequences of an Inherited Mutation at mRNA, Protein and Metabolic Levels, Biochemistry Journal, 2005. 392, 675-683.
“After printing to Full Moon BioSystems cDNA slides (Full Moon BioSystems, Sunnyvale, CA, USA), DNA was UV cross-linked to the slide…”

Ong C, Ooi CH, et al.: Patters of Large-scale Genomic Variation in Virulent and Avirulent Burkholderia Species, Genome Research 2004 14: 2295-2307.
“ …each array probe was printed in duplicate on commercially available microarray slides (Full Moon BioSystems) using an SDDC-2 Mcroarrayer (Virtek).”

Ou K, Ong K, et al.: Integrative Genomic, Transcriptional, and Proteomic Diversity in Natural Isolates of the Human Pathogen Bukholderia pseudomallei, Journal of Bacteriology, June 2005, p. 4273-4285.
“Probes, ranging from 300 to 1000 bp in length, were PCR amplified from K96243 genomic data and spotted in duplicate onto coated glass slides (Full Moon BioSystems).”

Ren D, Bedzyk L, et al.: Differential Gene Expression to Investigate the Effect of (5Z)-4-Bromo-5-(Bromomethylene)-3-Butyl-2(5H)-Furanone on Bacillus subtilis, Applied and Environmental Microbiology 2004, 70(8) 4941-4949.
“The double stranded PCR products were denatured in 50% dimethyl sulfoxide and spotted onto aminosilance slides (Full Moon BioSystems, Sunnyvale, Calif.) as probes to hybridize with the mRNA-derived cDNA samples.”
“The labeled cDNA (6 ug) was concentrated to 10 uL (total volume) and mixed with 10 uL of 4X cDNA hybridization solution (Full Moon BioSystems) and 20 uL of foramide.”

Rodrigues F, Sarkar-Tyson M, et al.: Global Map of Growth-Regulated Gene Expression in Burkholderia pseudomallei, the Causative Agent of Meloiodosis, Journal of Bacteriology, Dec. 2006, p. 8178-8188.
“Probes of 300 to 1000 bp in length were PCR amplified and spotted in duplicate onto coated glass slides (Full Moon BioSystems, Inc., Sunnyvale, CA).”

Russell S, FlyChip, University of Cambridge, UK, International Drosophila Array Consortium Forum
“We found that 150 mM NaPO[4] with … FMB PowerMatrix slides was best. We prefer PowerMatrix substrates because they are cheaper and more robust.”

Woodard C, Liao G, A Screen for Extracellular Signal-Regulated Kinase-Primed Glycogen Synthase Kinase 3 Substrates Identifies the p53 Inhibitor iASPP, Journal of Virology, 2015 89(18):9232-41 [PubMed]

Yang L, Wang J, Identification of serum biomarkers for gastric cancer diagnosis using a human proteome microarray, Molecular & Cellular Proteomics, 2015 Nov 23. pii: mcp.M115.051250 [PubMed]

Yauk CL, Williams A, et al.: Novel Design and Controls for Focused DNA Microarrays: Applications in Quality Assurance/Control and Normalization for the Health Canada ToxArrayä, BMC Genomics 2006, 7:266.
“Oligonucleotides were … printed unto PowerMatrix slides (Full Moon BioSystems, Sunnyvale, CA, USA) with the ChipWriter Pro robotic arrayer…”

Zheng D, Wan J, Comparison of Humoral Immune Responses to Epstein-Barr Virus and Kaposi’s Sarcoma–Associated Herpesvirus Using a Viral Proteome Microarray, Journal of Infect Dis. (2011) 204 (11): 1683-1691.