Selected Publications

Antibody Arrays

2016

Journals Array Platform
Gao Y, Bai X, Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis, Nat Struct Mol Biol 2016 23(5):441-9 [PubMed] Phospho Explorer Array
Garnett D, Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer, J Cancer Res Clin Oncol 2016, 142:611–618 [Springer] Signaling Explorer Antibody Array
Gruosso T, Mieulet V, Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients, EMBO Mol Med 2016 Mar 22. pii: e201505891. doi: 10.15252/emmm.201505891 [PubMed] Cell Cycle Control Phospho Antibody Array
Gu C, Feng M, RalA, a GTPase targeted by miR‑181a, promotes transformation and progression by activating the Ras‑related signaling pathway in chronic myelogenous leukemia, Oncotarget, 2016 Mar 8. doi: 10.18632/oncotarget.7987 [PubMed] Cancer Signaling Phospho Antibody Array
Gupta S, Manubhai KP, An overview of innovations and industrial solutions Portein Microarray Technology, Proteomics, 2016 April 4, doi: 10.1002/pmic.201500429 [Wiley]
Huang M, Lou D, Pyrrolidine dithiocarbamate attenuates paraquat-induced acute pulmonary poisoning in vivo via transforming growth factor β1 and nuclear factor κB pathway interaction, Hum Exp Toxicol 2016 Feb 9, pii: 0960327116630351 [PubMed] Phospho Explorer Array
Hwang HJ, Jung SH, Identification of novel therapeutic targets in the secretome of ionizing radiation‑induced senescent tumor cells, Oncol Rep, 2016 35(2):841-850 [Oncology Reports] Cytokine Profiling Array
Jiang HL, Sun HF, SSBP1 Suppresses TGF-β-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling, Cancer Res 2016 76(4):952-64 [PubMed] Phospho Explorer Array
Kuang XY, Jiang HS, The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis, Cancer Lett 2016 377(1):87-96 [PubMed] Phospho Explorer Array
Park HJ, Oh JS, Proton Irradiation Sensitizes Radioresistant Non-small Cell Lung Cancer Cells by Modulating Epidermal Growth Factor Receptor-mediated DNA Repair, Anticancer Res, 2016 36(1):205-12 [PubMed] Signaling Explorer Array
Pulito C, Sacconi A, Antibody Array as a Tool for Screening of Natural Agents in Cancer Chemoprevention, Methods Mol Biol, 2016 1379:189-99 [PMC] Phospho Explorer Array
Shah A, Kannambath S, Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus During Macrophage Cell Death, Am J Respir Crit Care Med, 2016 May 10 [PubMed] Phospho Explorer Array
Tan X, Liu P, Phosphoproteome Analysis of Invasion and Metastasis-Related Factors in Pancreatic Cancer Cells, PLOS One, 2016 March 25, DOI: 10.1371/journal.pone.0152280 [PLOS One] Phospho Explorer Array
Xu J, Zhou L, The REGγ-proteasome forms a regulatory circuit with IκBε and NFκB in experimental colitis, Nat Commun, 2016 Feb 7:10761 [PMC] Phospho Explorer Array
Yang T, Yao H, Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis, Journal of Cancer 2016; 7(2): 192-199 [PDF] Explorer Antibody Array
Zhu Y, Dai B, Long non-coding RNA LOC572558 inhibits bladder cancer cell proliferation and tumor growth by regulating the AKT-MDM2-p53 signaling axis, Cancer Lett, 2016 Apr 26, doi:10.1016/j.canlet.2016.04.030 [PubMed] Cancer Signaling Phospho Antibody Array
Zhu R, Wang Q, pH sensitive nano layered double hydroxides reduce the hematotoxicity and enhance the anticancer efficacy of etoposide on non-small cell lung cancer, Acta Biomater, 2016 29:320-332 [PubMed] Cancer Signaling Phospho Antibody Array

 2015

Journals Array Platform
Arsenault RJ, Genovese KJ, Wild-type and mutant AvrA−Salmonella induce broadly similar immune pathways in the chicken ceca with key differences in signaling intermediates and inflammation, Poult Sci 2015 Nov 14. pii: pev344 [PubMed]  Phospho Explorer Array
de la Encarnacion A, Alqueza C, Increased Wnt Signaling and Reduced Viability in a Neuronal Model of Progranulin-Deficient Frontotemporal Lobar Degeneration, Mol Neurobiol, First online: 17 December 2015 [Springer] WNT Phospho Antibody Array
Eke I, Hehlgans S, Comprehensive analysis of signal transduction in three-dimensional ECM-based tumor cell cultures, J Biol Methods 2015; 2(4): e31 [PMC] Phospho Explorer Array
Eke I, Zscheppang K, Simultaneous β1 integrin-EGFR Targeting and Radiosensitization of Human Head and Neck Cancer, J Natl Cancer Inst (2015) 107(2): dju419 [PubMed] Phospho Explorer Array
Gavine P, Wang M, Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma, BMC Cancer, 2015 Jun 4;15:454 [PubMed] Phospho Explorer Array
Genebai N, Ahmad S, Genetic inhibition of JNK3 ameliorates spinal muscular atrophy, Hum Mol Genet, 2015 Sep 30. pii:ddv401 [PubMed] MAPK Phospho Antibody Array
Guo J, Wang Q, Visible red and infrared light alters gene expression in human marrow stromal fibroblast cells, Orthod Craniofac Res, 2015 18(Suppl.1):50–61 [PubMed] TGF-beta Phospho Antibody Array
Gutierrez CM, Lopez-Valdez R, A Breast Tissue Protein Expression Profile Contributing to Early Parity-Induced Protection Against Breast Cancer, Cell Physiol Biochem 2015 37(5):1671-1685 [PubMed] Phospho Explorer Array
Hasan M, Neumann B, Activation of TGF-β-induced non-Smad signaling pathways during Th17 differentiation, Immunol Cell Biol, 2015 Aug;93(7):662-72 [PubMed] TGF-beta Phospho Antibody Array
Havel LS, Kline ER, Vimentin regulates lung cancer cell adhesion through a VAV2–Rac1 pathway to control focal adhesion kinase activity, Oncogene, 2015 Apr 9;34(15):1979-90 [PubMed] Phospho Explorer Array
Kim, SY, Han YM, DUSP4 regulates neuronal differentiation and calcium homeostasis by modulating ERK1/2 phosphorylation, Stem Cells Dev, 2015 Mar 15;24(6):686-700 [PubMed] WNT Phospho Antibody Array
Kogut MH, Arsenault RJ, A Role for the Non-Canonical Wnt-β-Catenin and TGF-β Signaling Pathways in the Induction of Tolerance during the Establishment of a Salmonella enterica Serovar Enteritidis Persistent Cecal Infection in Chickens, Front Vet Sci, 2015; 2: 33 [PMC] WNT Phospho Antibody Array
Lee MS, Kim JH, Prognostic Significance of CREB-Binding Protein and CD81 Expression in Primary High Grade Non-Muscle Invasive Bladder Cancer: Identification of Novel Biomarkers for Bladder Cancer Using Antibody Microarray, PLoS One, 2015 10(4):e0125405 [PubMed] Explorer Antibody Array
Li W, Zhang C, Withaferin A suppresses the up-regulation of acetyl-coA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse model, Mol Carcinog, 2015 Oct 16, doi: 10.1002/mc.22423 [PubMed] Phospho Explorer Array
Li Z, Younger K, Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies, J Clin Invest, 2015 125(3):1081–97 [PubMed] Customized Antibody Array
Lund R, Leth-Larsen R, NADH-cytochrome b5 reductase 3 promotes colonization and metastasis formation and is a prognostic marker of disease-free and overall survival in estrogen receptor-negative breast cancer, Mol Cell Proteomics, 2015 14(11):2988-99 [PubMed] Signaling Explorer Antibody Array
Luo L, Zhao L, Insulin-like growth factor binding protein-3 is a new predictor of radiosensitivity on esophageal squamous cell carcinoma, Sci Rep, 2015; 5: 17336 [PMC] Phospho Explorer Array
Luo MXM, Wong SH, Autophagy Mediates HBx-Induced Nuclear Factor-κB Activation and Release of IL-6, IL-8 and CXCL2 in Hepatocytes, J Cell Physiol, 2015 230(10):2382-9 [PubMed] Cytokine Profiling Antibody Array
Oldefest M, Düsterhöft S, Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of Interleukin-6 receptor release by A disintegrin and Metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3, Biochem J, 2015 468(3):507-18 [PubMed] WNT Phospho Explorer Antibody Array
Pulito C, Mori F, Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion, Oncotarget, 2015 6(20):18134-50 [PMC] Phospho Explorer Array
Rosenfeld S, Rich J, Mitotic Kinesin Eg5 Inhibiting Anticancer Agents, US Patent Application 20150352114 Cytoskeleton Phospho Antibody Array
Shigyo M, Kuboyama T, Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth, Scientific Reports 5:12055 (2015) Phospho Explorer Array
Sobol A, Galluzzo P, Depletion of Amyloid Precursor Protein (APP) Causes G0 Arrest in Non-Small Cell Lung Cancer (NSCLC) Cells, J Cell Physiol, 2015 230(6):1332–41 [PubMed] Cell Cycle Phospho Antibody Array
Takahashi T, Uehara H, Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-θ activation, Oncotarget, 2015 6(7):4826-44 [PMC] Phospho Explorer Array
Uckun, FM, Mitchell L, Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL, EBioMedicine July 2015;2(7):649–59 Phospho Explorer Array
Vettorazzi S, Bode C, Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1, Nat Commun, 2015 6:7796 [PMC] Phospho Explorer Array
Wan F, Qin X, Oxidized low-density lipoprotein is associated with advanced-stage prostate cancer, Tumor Biology, 2015 36(5):3573-82 [PubMed] Phospho Explorer Array
Zhu Y, Wan F, Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth, Oncotarget 2015 Jun 10; 6(16): 14488–14496 [PMC] Cancer Signaling Phospho Antibody Array

Scanner Calibration Slides

Lee JK., Heimer BW, Systematic study of fluorescein-functionalized macrophotoinitiators for colorimetric bioassays, Biomacromolecules 13.4 (2012): 1136-1143

Risinger A, Williams C: ScanArray Gx Plus/ProScanArray Competitive Performance Analysis Using a Commercial Test Slide, Application Note, PerkinElerm Life and Analytical Sciences, Shelton, CT, USA, www.perkinelmer.com.
“The Full Moon BioSystems All Purpose Scanner Evaluation Slide (Prod # AV05) was used to perform these experiments…”

Shi L, Tong W, et al.: Microarray Scanner Calibration Curves: Characteristics and Implications, BMC Bioinformatics 2005, 6(Suppl 2):S11.
“The microarray scanner calibration slide from Full Moon BioSystems Inc. (Sunnyvale, CA, USA) has been developed for performing quantitative evaluations microarray scanners in terms of dynamic range, limit of detection, uniformity of microarray scanners, channel-to-channel cross-talk, and laser stability.”

Wang L, Gaigalas A, et al.: Effect of Target and Probe Concentrations on Hybridization in DNA Microarrays, Microarray and Combinatorial Techniques: Design, Fabrication, and Analysis II. Edited by Nicolau, Dan V; Raghavachari, Ramesh. Proceeding of the SPIE, Vol. 5328, pp. 129-139 (2004).
“Scanner Calibration Slides (manufactured by Full Moon BioSystems) were used to concert the fluorescence signals into fluorophore per um2 in order eliminate possible variation from scanner.”

Zhang Y, Milam VT, et al.: Differential Adhesion of Microspheres Mediated by DNA Hybridization I: Experiment, Biophysical Journal, 90:4128-4136 (2006).
“The slides are then scanner with ScanArray 5000 (PerkinElmer Life and Analytical Sciences, Wellesley, MA) and the fluorescent intensity is compared with that of a calibration slide (Full Moon BioSystems, Sunnyvale, CA).”

Microarray Slides

Chen C, Korobkova E, et al.: A Proteome Chip Approach Reveals New DNA Damage Recognition Activities in Escherichia coli, Nature Methods, 5 (1), Jan. 2008.
“Different surface chemistries were tested, including the FullMoon, aldehyde-derivatized, hydrogel- and nitrocellulose-coated (FAST slides) surfaces. All of the tests produced satisfactory immobilization results, with the FullMoon surfaces performing the best.” ”
“To optimize the binding conditions, we carried out a series of pilot assays and determined that the FullMoon surface produced the best signal-to-noise ratio with a stringent high-salt wash.”

Covarrubia MY, Khan R, et al.: Chronic Alcohol Exposure Alters Transcription Broadly in a Key Integrative Brain Nucleus for Homeostasis: the nucleus tracus solitarius, Physiological Genomics 2005.
“cDNA were mixed with an equal volume of DMSO (10-70 ng/ul) and printed on FMB cDNA slides (Full Moon BioSystems, Sunnyvale, CA) using a MicroGrid II arrayer…”

Dhar MS, Yuan JS, et al.: A Type IV P-Type ATPase Affects Insulin-mediated Glucose Uptake in Adipose Tissue and Skeletal Muscle in Mice, Journal of Nutritional Biochemistry, 17 (12), 811-820 (2007).
“The mouse whole genome long-oligo set was printed on the PowerMatrix Slides (Full Moon BioSystems, Sunnyvale, CA, USA).”

Ding M, Gao Q, et al.: Construction and Validation of an Insecticide Resistence-Associated DNA Microarray, Journal Pesticide Science 2007, 32(1), 32-41
“…the diluted products were spotted onto FMB slides (Full Moon BioSystems) using a robotic spotting system (GeneMachine).”

Ellestad LE, Carre W, et al.: Gene Expression Profiling During Cellular Differentiation in the Embryonic Pituitary Gland Using cDNA Microarrays, Physical Genomics 2006, 25: 414-425.
“PCR products were rearrayed into 384-well plates in 50% DMSO and printed onto glass microscope slides (Full Moon BioSystems, Sunnyvale, CA) as high-density cDNA microarrays at Delaware Biotechnology Institute…”

Gardiner JM, Buell CR, Design, Production, and Utilization of Long Oligonucleotide Microarrays for Expression Analysis in Maize, Maydica 2005 50: 425-435.
“The long oligo microarrays were spotted on …specially coated PowerMatrix slides (Full Moon BioSystems, Sunnyvale, CA)…”

Gertych , Oh JH, 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models, BMC Pharmacology and Toxicology 2013, 14:11

Horiuchi KY, Wang Y, Microarray for the Functional Analysis of the Chemica-Kinase Interactome, Journal of Biomolecular Screening X(X); 2006.
“Protein slides to immobilize proteins were purchased from Full Moon BioSystems (Sunnyvale, CA).” … “Full Moon BioSystems Protein slides were found to bind up to 500 nM of MEK in the printing solution (compared to 300 nM on the epoxy slide).”

Huang R, Lin Y, Enhanced Protein Profiling Arrays with ELISA-Based Amplification for High-Throughput Molecular Changes of Tumor Patients’ Plasma, Clinical Cancer Research, 2004 10: 598-609.
“One of the advance technologies in protein arrays is the three-dimensional substrate chip. To test whether our system can also be sued to enhance detection sensitivity in three-dimensional substrate chips from Full Moon BioSystems (Sunnyvale, CA)…”

Olah J, Orosz F, et al.: Triosephosphate Isomerase Deficiency: Consequences of an Inherited Mutation at mRNA, Protein and Metabolic Levels, Biochemistry Journal, 2005. 392, 675-683.
“After printing to Full Moon BioSystems cDNA slides (Full Moon BioSystems, Sunnyvale, CA, USA), DNA was UV cross-linked to the slide…”

Ong C, Ooi CH, et al.: Patters of Large-scale Genomic Variation in Virulent and Avirulent Burkholderia Species, Genome Research 2004 14: 2295-2307.
“ …each array probe was printed in duplicate on commercially available microarray slides (Full Moon BioSystems) using an SDDC-2 Mcroarrayer (Virtek).”

Ou K, Ong K, et al.: Integrative Genomic, Transcriptional, and Proteomic Diversity in Natural Isolates of the Human Pathogen Bukholderia pseudomallei, Journal of Bacteriology, June 2005, p. 4273-4285.
“Probes, ranging from 300 to 1000 bp in length, were PCR amplified from K96243 genomic data and spotted in duplicate onto coated glass slides (Full Moon BioSystems).”

Ren D, Bedzyk L, et al.: Differential Gene Expression to Investigate the Effect of (5Z)-4-Bromo-5-(Bromomethylene)-3-Butyl-2(5H)-Furanone on Bacillus subtilis, Applied and Environmental Microbiology 2004, 70(8) 4941-4949.
“The double stranded PCR products were denatured in 50% dimethyl sulfoxide and spotted onto aminosilance slides (Full Moon BioSystems, Sunnyvale, Calif.) as probes to hybridize with the mRNA-derived cDNA samples.”
“The labeled cDNA (6 ug) was concentrated to 10 uL (total volume) and mixed with 10 uL of 4X cDNA hybridization solution (Full Moon BioSystems) and 20 uL of foramide.”

Rodrigues F, Sarkar-Tyson M, et al.: Global Map of Growth-Regulated Gene Expression in Burkholderia pseudomallei, the Causative Agent of Meloiodosis, Journal of Bacteriology, Dec. 2006, p. 8178-8188.
“Probes of 300 to 1000 bp in length were PCR amplified and spotted in duplicate onto coated glass slides (Full Moon BioSystems, Inc., Sunnyvale, CA).”

Russell S, FlyChip, University of Cambridge, UK, International Drosophila Array Consortium Forum
“We found that 150 mM NaPO[4] with … FMB PowerMatrix slides was best. We prefer PowerMatrix substrates because they are cheaper and more robust.”

Woodard C, Liao G, A Screen for Extracellular Signal-Regulated Kinase-Primed Glycogen Synthase Kinase 3 Substrates Identifies the p53 Inhibitor iASPP, Journal of Virology, 2015 89(18):9232-41 [PubMed]

Yang L, Wang J, Identification of serum biomarkers for gastric cancer diagnosis using a human proteome microarray, Molecular & Cellular Proteomics, 2015 Nov 23. pii: mcp.M115.051250 [PubMed]

Yauk CL, Williams A, et al.: Novel Design and Controls for Focused DNA Microarrays: Applications in Quality Assurance/Control and Normalization for the Health Canada ToxArrayä, BMC Genomics 2006, 7:266.
“Oligonucleotides were … printed unto PowerMatrix slides (Full Moon BioSystems, Sunnyvale, CA, USA) with the ChipWriter Pro robotic arrayer…”

Zheng D, Wan J, Comparison of Humoral Immune Responses to Epstein-Barr Virus and Kaposi’s Sarcoma–Associated Herpesvirus Using a Viral Proteome Microarray, Journal of Infect Dis. (2011) 204 (11): 1683-1691.