| Product Name | JAK3 Rabbit mAb |
| Background | The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008] |
| Reactivity | Human |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IF; IP; ELISA |
| Dilutions | WB: 1:1000-1:5000; IHC: /; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 125; Observed: 125 |
| UniProt Accession # | P52333 |
| Protein Name | JAK3 |
| Gene Name | JAK3 |
| Gene ID | 3718 |
| Other Names | JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK |