| Product Name | EEA1 Rabbit mAb |
| Background | Disease: Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. Domain: The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Similarity: Contains 1 C2H2-type zinc finger. Similarity: Contains 1 FYVE-type zinc finger. Subunit: Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IHC; IF; IP; ELISA |
| Dilutions | WB: 1:1000-1:5000; IHC: 1:100-1:200; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 162; Observed: 162 |
| UniProt Accession # | Q15075 |
| Protein Name | EEA1 |
| Gene Name | EEA1 |
| Gene ID | 8411 |
| Other Names | EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2 |