| Product Name | c-Jun Rabbit mAb |
| Background | Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Post-Translational Modification (PTM): Phosphorylation enhances transcriptional activity. It is phosphorylated by PRKDC. Similarity: Belongs to the bZIP family, specifically the Jun subfamily. Contains one bZIP domain. Subunit: Forms a heterodimer with either FOS or BATF3. Interacts with HIVEP3 (by similarity). Also interacts with SMAD3/SMAD4 heterodimers, MYBBP1A, SPIB, and TCF20. Additionally, it interacts with COPS5, indirectly leading to its phosphorylation. Interacts with DSIPI, which inhibits the binding of active AP1 to its target DNA. |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IHC; IF; IP; ELISA |
| Dilutions | WB: 1:2000-1:10000; IHC: 1:200-1:1000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 36; Observed: 43 |
| UniProt Accession # | P05412 |
| Protein Name | c-Jun |
| Gene Name | JUN |
| Gene ID | 3725 |
| Other Names | Transcription factor AP-1 (Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39) |