SELECTED PUBLICATIONS

JournalArray Platform
Amitrano A, Berry B, Optical Control of CD8 + T Cell Metabolism and Effector Functions, Front Immunol. 2021 Jun 3;12:666231. doi: 10.3389/fimmu.2021.666231Cytokeleton Phospho Array
Anita L, Yin GN, Pericyte-derived extracellular vesicle-mimetic nanovesicles ameliorate erectile dysfunction via lipocalin 2 in diabetic mice, Int J Biol Sci 2022; 18(9):3653-3667. doi:10.7150/ijbs.72243Signaling Explorer Array
Anerillas C, Herman A, Early SRC activation skews cell fate from apoptosis to senescence, Sci. Adv. 8 (14):eabm0756. DOI: 10.1126/sciadv.abm0756Phospho Explorer Array
Bae YU, You JH, Association of Protein Z with Prediabetes and Type 2 Diabetes, Endocrinol Metab (Seoul). 2021 Jun 2.  doi: 10.3803/EnM.2021.962Cytokine Profiling Array
Beck AC, Cho E, AP-2alpha Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer, Mol Cancer Res March 22 2021 DOI: 10.1158/1541-7786.MCR-20-0867Cell Cycle Phospho Array
Boix O, Martinez M, pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation, Nat Commun. 2022 Nov 11;13(1):6840. doi: 10.1038/s41467-022-34529-6Phospho Cytoskeleton Array
Chalise U, Becirovic-Agic, MMP-12 polarizes the neutrophil signalome towards an apoptotic signature, J. Proteomics. 2022. https://doi.org/10.1016/j.jprot.2022.104636Cell Signaling Phospho Array
Chesnokova LS, Mosher B, Distinct early role of PTEN regulation during HCMV infection of monocytes. PNAS 2024 Mar 19;121(12):e2312290121. doi: 10.1073/pnas.231229012Phospho Explorer Array
Chesnokova LS, Yurochko AD (2021) Using a Phosphoproteomic Screen to Profile Early Changes During HCMV Infection of Human Monocytes. In: Yurochko A.D. (eds) Human Cytomegaloviruses. Methods in Molecular Biology, vol 2244. Humana, New York, NYPhospho Explorer Array
Daneshmandi S, Choi JE, Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies, Nat Commun. 2024; 15: 2803. doi: 10.1038/s41467-024-47096-9Apoptosis Phospho Antibody Array
Deng Y, Zeng X, Cdyl2-60aa encoded by CircCDYL2 accelerates cardiomyocyte death by blocking APAF1 ubiquitination in rats, Exp Mol Med. 2023 Apr 3. doi: 10.1038/s12276-023-00983-5Apoptosis Phospho Antibody Array
Falcomata C, Bartehl S, Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment, Nat Cancer. 2022 Jan 31. doi: 10.1038/s43018-021-00326-1Phospho Explorer Array
Ghosh D, Pham TD, Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells, Cell Rep. 2022 Jan 25;38(4):110200T-Cell Receptor Phospho Array
Howell MC Jr, Green R, EGFR TKI resistance in lung cancer cells using RNA sequencing and analytical bioinformatics tools, J Biomol Struct Dyn. 2022 Dec 16;1-20. doi: 10.1080/07391102.2022.2153269Phospho Explorer Array
Hwang HJ, Kang D, FLRT2 prevents endothelial cell senescence and vascular aging by regulating the ITGB4/mTORC2/p53 signaling pathway, JCI Insight. 2024 Apr 8;9(7):e172678. doi: 10.1172/jci.insight.172678Phospho Explorer Array
Jiang R, Smailovic U, Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's A? amyloidosis, Acta Neuropathol Commun. 2022 Jul 4;10(1):96. doi: 10.1186/s40478-022-01398-5Phospho Explorer Array
Kang SH, Oh SY. Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p. Theranostics. 2024 Jan 1;14(2):460-479. doi: 10.7150/thno.87329Cytokine Profiling Array
Kattih B, Boeckling F, Single-nuclear transcriptome profiling identifies persistent fibroblast activation in hypertrophic and failing human hearts of patients with longstanding disease, Cardiovasc Res. 2023 Aug 30;cvad140. doi: 10.1093/cvr/cvad140TGFb Phospho Array
Kim DH, Cho HJ, Transplantation of PSA-NCAM-Positive Neural Precursors from Human Embryonic Stem Cells Promotes Functional Recovery in an Animal Model of Spinal Cord Injury, Tissue Eng Regen Med. 2022 Aug 29. doi: 10.1007/s13770-022-00483-zCytokine Antibody Array
Kim HA, Baek KJ, Integrative proteomic network analyses support depot?specific roles for leucine rich repeat LGI family member 3 in adipose tissues. Exp Ther Med. 2021. 22:837. https://doi.org/10.3892/etm.2021.10269"Phospho Explorer Array
Kim HJ, Choi EW, Non-thermal plasma promotes hair growth by improving the inter-follicular macroenvironment. RSC Adv. 2021. 11:27880-27896Signaling Explorer Array
Kiso-Farne K, Tsuruyama T, Epidermal growth factor receptor cascade prioritizes the maximization of signal transduction. Sci Rep. 2022 Oct 10;12(1):16950EGF Phospho Array
MAPK Phospho Array
Kurzava KL, Ma Y, Epigenetic Effects of Resveratrol on Oncogenic Signaling in Breast Cancer. Nutrients. 2024; 16(5):699. https://doi.org/10.3390/nu16050699Phospho Explorer Array
Lee Jh, Chung MY, Anacardic Acid Suppresses Adipogenesis Through Inhibition of the Hsp90/Akt Signaling Pathway in 3T3-L1 Preadipocytes. J Med Food 2021 24:5; 487-496Signaling Explorer Array
Lee M, PSAT157 Efficacy of Bisphosphanate Treatment in Pediatric Patients with Osteoporosis Due to Immobilization, Journal of the Endocrine Society Volume 6; Issue Supplement_1. November-December 2022. Page A197. https://doi.org/10.1210/jendso/bvac150.405"GPCR Phospho Array
Lim HS, Sohn E, Ethanol Extract of Elaeagnus glabra f. oxyphylla Branches Alleviates the Inflammatory Response Through Suppression of Cyclin D3/Cyclin-Dependent Kinase 11p58 Coupled to Lipopolysaccharide-Activated BV-2 Microglia, Natural Product Comm. January 2022. doi:10.1177/1934578X22107507Phospho Explorer Array
Liu J, Yu L, Short-term tetrabromobisphenol A exposure promotes fibrosis of human uterine fibroid cells in a 3D culture system through TGF-beta signaling, FASEB J. 2022 Feb;36(2):e22101TGFb Phospho Array
Lutz AK, Arevalo AP, SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(?/?) Mice. Front. Mol. Neurosci. 26 November 2021. https://doi.org/10.3389/fnmol.2021.773571ERK Phospho Array
Mathison A, Kerketta R, Kras-G12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells. Genome Biol 2021; 22:289. https://doi.org/10.1186/s13059-021-02498-6Cancer Signaling Phospho Array
Müller, A., Lozoya, M., Farnesol Inhibits PI3 Kinase Signaling and Inflammatory Gene Expression in Primary Human Renal Epithelial Cells. Biomedicines 2023. 11:3322. doi.org/10.3390/biomedicines11123322TGFb Phospho Array
Odeh A, Eddini H, Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response, Int. J. Mol. Sci. 2023. 24(6): 5132; https://doi.org/10.3390/ijms24065132NFkB Phospho Antibody Array
Peaslee, C, Esteva?Font, C, Doxycycline Significantly Enhances Induction of iPSCs to Endoderm by Enhancing survival via AKT Phosphorylation. Hepatology 2021. Accepted Author Manuscript. https://doi.org/10.1002/hep.31898Phospho Explorer Array
Rafi SK, Goering JP, Anti-epileptic drug topiramate upregulates TGF?1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity. PLoS ONE  2021. 16(2): e0246989,Signaling Explorer Array
Ravishankar P, Dail A, Tears as the Next Diagnostic Biofluid: A Comparative Study between Ocular Fluid and Blood, Appl. Sci. 2022. 12(6):2884; https://doi.org/10.3390/app12062884,Explorer Antibody Array
Cancer BioMarker Array
Sankar A, Cho HM, Antibody-drug conjugate ?EGFR-E-P125A reduces triple-negative breast cancer vasculogenic mimicry, motility, and metastasis through inhibition of EGFR, integrin, and FAK/STAT3 signaling, Cancer Res Commun. 2024 Feb 5. doi: 10.1158/2767-9764.CRC-23-0278Phospho Explorer Array
Santerre K, Ghio SC, TGF-?-Mediated Modulation of Cell-Cell Interactions in Postconfluent Maturing Corneal Endothelial Cells, Invest Ophthalmol Vis Sci. 2022 Oct 3;63(11):3.  doi: 10.1167/iovs.63.11.3TGFb Phospho Array
Schatton, T, Itoh Y, Inhibition of melanoma cell-intrinsic Tim-3 stimulates MAPK-dependent tumorigenesis, Cancer Res. 2022 Aug 18;CAN-22-0970. doi: 10.1158/0008-5472.CAN-22-0970Phospho Explorer Array
Sebastian S, Weinstein L, Slowing heart rate protects against pathological cardiac hypertrophy, Function. 2022: zqac055ERK Phospho Array
Shin E, Kim D, LDR-adapted liver-derived cytokines have potential to induce atherosclerosis, Int J Radiat Biol. 2022. DOI: 10.1080/09553002.2023.2145028Cytokine Profiling Array
Singh MV, Wong T, BLNK/BTK: Novel Components in the NF-kappa B Pathways of Endothelial Cells in Diabetic Condition. J Endocr Soc. 2021;5(Suppl 1):A318-A319. Published 2021 May 3. doi:10.1210/jendso/bvab048.649NFkB Phospho Array
Song H, Yang Y, Tripeptide Hyp-Asp-Gly from collagen peptides inhibited platelet activation via regulation of PI3K/Akt-MAPK/ERK1/2 signaling pathway, J Food Sci. 2022 Jun 15. doi: 10.1111/1750-3841.16215GPCR Phospho Array
Sun X, Chen M, Knockdown of KIF15 promotes cell apoptosis by activating crosstalk of multiple pathways in ovarian cancer: bioinformatic and experimental analysis, Int J Clin Exp Pathol. 2021 Feb 1;14(2):267-291Cell Signaling Phospho Array
Tsuruyama T, Kullback–Leibler Divergence of an Open-Queuing Network of a Cell-Signal-Transduction Cascade, Entropy 2023. 25(2):326; https://doi.org/10.3390/e25020326EGF Phospho Array
MAPK Phospho Array
Urena F, Ma C, T cell activation decreases microRNA-15a/16 levels to promote MEK1-ERK1/2-Elk1 signaling and promote proliferative capacity, J Biol Chem. 2022 Jan 25;298(3):101634. doi:10.1016/j.jbc.2022.101634ERK Phospho Array
Vargas B, Boslett J, Mechanism by Which PF-3758309, a Pan Isoform Inhibitor of p21-Activated Kinases, Blocks Reactivation of HIV-1 Latency. Biomolecules. 2023; 13(1):100. https://doi.org/10.3390/biom13010100Phospho Explorer Array
Watson D, Bayik D, GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity, Nat Cancer. 2023 May 11. doi: 10.1038/s43018-023-00556-5Phospho Explorer Array
Yamada S, Yassin M, Unique osteogenic profile of bone marrow stem cells stimulated in perfusion bioreactor is Rho-ROCK-mediated contractility dependent, Bioeng Transl Med. 2023;e10509. doi:10.1002/btm2.10500Cytoskeleton Phospho Array
Xie X, Lv H, HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis, BMC Med. 2021; 19:247. https://doi.org/10.1186/s12916-021-02085-3Phospho Explorer Array
Ye Q, Chen H, Abnormal expression of p-ATM/CHK2 in nasal extranodal NK/T cell lymphoma, nasal type, is correlated with poor prognosis, J Clin Pathol. 2021 Apr. 74(4):223-227Cell Cycle Array
Yin GN, Kim DK, Latrophilin-2 is a novel receptor of LRG1 that rescues vascular and neurological abnormalities and restores diabetic erectile function, Exp Mol Med. 2022 May 13. doi: 10.1038/s12276-022-00773-5Phospho Explorer Array
You KS, Yi, YW, Dual Inhibition of AKT and MEK Pathways Potentiates the Anti-Cancer Effect of Gefitinib in Triple-Negative Breast Cancer Cells. Cancers 2021. 13(6): 1205Phospho Explorer Array
Yoon N, Lee H, A Metabolomics Investigation of the Metabolic Changes of Raji B Lymphoma Cells Undergoing Apoptosis Induced by Zinc Ions, Metabolites 2021. 11(10): 689Phospho Explorer Array
Zhao Y, Zhu W, Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in mice, Nat Commun. 2022 Nov 10;13(1):6813. doi: 10.1038/s41467-022-34293-7Signaling Explorer Array

Lee JK., Heimer BW, Systematic study of fluorescein-functionalized macrophotoinitiators for colorimetric bioassays, Biomacromolecules 13.4 (2012): 1136-1143

Risinger A, Williams C: ScanArray Gx Plus/ProScanArray Competitive Performance Analysis Using a Commercial Test Slide, Application Note, PerkinElerm Life and Analytical Sciences, Shelton, CT, USA, www.perkinelmer.com.
“The Full Moon BioSystems All Purpose Scanner Evaluation Slide (Prod # AV05) was used to perform these experiments…”

Shi L, Tong W, et al.: Microarray Scanner Calibration Curves: Characteristics and Implications, BMC Bioinformatics 2005, 6(Suppl 2):S11.
“The microarray scanner calibration slide from Full Moon BioSystems Inc. (Sunnyvale, CA, USA) has been developed for performing quantitative evaluations microarray scanners in terms of dynamic range, limit of detection, uniformity of microarray scanners, channel-to-channel cross-talk, and laser stability.”

Wang L, Gaigalas A, et al.: Effect of Target and Probe Concentrations on Hybridization in DNA Microarrays, Microarray and Combinatorial Techniques: Design, Fabrication, and Analysis II. Edited by Nicolau, Dan V; Raghavachari, Ramesh. Proceeding of the SPIE, Vol. 5328, pp. 129-139 (2004).
“Scanner Calibration Slides (manufactured by Full Moon BioSystems) were used to concert the fluorescence signals into fluorophore per um2 in order eliminate possible variation from scanner.”

Zhang Y, Milam VT, et al.: Differential Adhesion of Microspheres Mediated by DNA Hybridization I: Experiment, Biophysical Journal, 90:4128-4136 (2006).
“The slides are then scanner with ScanArray 5000 (PerkinElmer Life and Analytical Sciences, Wellesley, MA) and the fluorescent intensity is compared with that of a calibration slide (Full Moon BioSystems, Sunnyvale, CA).”

Chen C, Korobkova E, et al.: A Proteome Chip Approach Reveals New DNA Damage Recognition Activities in Escherichia coli, Nature Methods, 5 (1), Jan. 2008.
“Different surface chemistries were tested, including the FullMoon, aldehyde-derivatized, hydrogel- and nitrocellulose-coated (FAST slides) surfaces. All of the tests produced satisfactory immobilization results, with the FullMoon surfaces performing the best.” ”
“To optimize the binding conditions, we carried out a series of pilot assays and determined that the FullMoon surface produced the best signal-to-noise ratio with a stringent high-salt wash.”

Covarrubia MY, Khan R, et al.: Chronic Alcohol Exposure Alters Transcription Broadly in a Key Integrative Brain Nucleus for Homeostasis: the nucleus tracus solitarius, Physiological Genomics 2005.
“cDNA were mixed with an equal volume of DMSO (10-70 ng/ul) and printed on FMB cDNA slides (Full Moon BioSystems, Sunnyvale, CA) using a MicroGrid II arrayer…”

Dhar MS, Yuan JS, et al.: A Type IV P-Type ATPase Affects Insulin-mediated Glucose Uptake in Adipose Tissue and Skeletal Muscle in Mice, Journal of Nutritional Biochemistry, 17 (12), 811-820 (2007).
“The mouse whole genome long-oligo set was printed on the PowerMatrix Slides (Full Moon BioSystems, Sunnyvale, CA, USA).”

Ding M, Gao Q, et al.: Construction and Validation of an Insecticide Resistence-Associated DNA Microarray, Journal Pesticide Science 2007, 32(1), 32-41
“…the diluted products were spotted onto FMB slides (Full Moon BioSystems) using a robotic spotting system (GeneMachine).”

Ellestad LE, Carre W, et al.: Gene Expression Profiling During Cellular Differentiation in the Embryonic Pituitary Gland Using cDNA Microarrays, Physical Genomics 2006, 25: 414-425.
“PCR products were rearrayed into 384-well plates in 50% DMSO and printed onto glass microscope slides (Full Moon BioSystems, Sunnyvale, CA) as high-density cDNA microarrays at Delaware Biotechnology Institute…”

Gardiner JM, Buell CR, Design, Production, and Utilization of Long Oligonucleotide Microarrays for Expression Analysis in Maize, Maydica 2005 50: 425-435.
“The long oligo microarrays were spotted on …specially coated PowerMatrix slides (Full Moon BioSystems, Sunnyvale, CA)…”

Gertych , Oh JH, 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models, BMC Pharmacology and Toxicology 2013, 14:11

Horiuchi KY, Wang Y, Microarray for the Functional Analysis of the Chemica-Kinase Interactome, Journal of Biomolecular Screening X(X); 2006.
“Protein slides to immobilize proteins were purchased from Full Moon BioSystems (Sunnyvale, CA).” … “Full Moon BioSystems Protein slides were found to bind up to 500 nM of MEK in the printing solution (compared to 300 nM on the epoxy slide).”

Huang R, Lin Y, Enhanced Protein Profiling Arrays with ELISA-Based Amplification for High-Throughput Molecular Changes of Tumor Patients’ Plasma, Clinical Cancer Research, 2004 10: 598-609.
“One of the advance technologies in protein arrays is the three-dimensional substrate chip. To test whether our system can also be sued to enhance detection sensitivity in three-dimensional substrate chips from Full Moon BioSystems (Sunnyvale, CA)…”

Olah J, Orosz F, et al.: Triosephosphate Isomerase Deficiency: Consequences of an Inherited Mutation at mRNA, Protein and Metabolic Levels, Biochemistry Journal, 2005. 392, 675-683.
“After printing to Full Moon BioSystems cDNA slides (Full Moon BioSystems, Sunnyvale, CA, USA), DNA was UV cross-linked to the slide…”

Ong C, Ooi CH, et al.: Patters of Large-scale Genomic Variation in Virulent and Avirulent Burkholderia Species, Genome Research 2004 14: 2295-2307.
“ …each array probe was printed in duplicate on commercially available microarray slides (Full Moon BioSystems) using an SDDC-2 Mcroarrayer (Virtek).”

Ou K, Ong K, et al.: Integrative Genomic, Transcriptional, and Proteomic Diversity in Natural Isolates of the Human Pathogen Bukholderia pseudomallei, Journal of Bacteriology, June 2005, p. 4273-4285.
“Probes, ranging from 300 to 1000 bp in length, were PCR amplified from K96243 genomic data and spotted in duplicate onto coated glass slides (Full Moon BioSystems).”

Ren D, Bedzyk L, et al.: Differential Gene Expression to Investigate the Effect of (5Z)-4-Bromo-5-(Bromomethylene)-3-Butyl-2(5H)-Furanone on Bacillus subtilis, Applied and Environmental Microbiology 2004, 70(8) 4941-4949.
“The double stranded PCR products were denatured in 50% dimethyl sulfoxide and spotted onto aminosilance slides (Full Moon BioSystems, Sunnyvale, Calif.) as probes to hybridize with the mRNA-derived cDNA samples.”
“The labeled cDNA (6 ug) was concentrated to 10 uL (total volume) and mixed with 10 uL of 4X cDNA hybridization solution (Full Moon BioSystems) and 20 uL of foramide.”

Rodrigues F, Sarkar-Tyson M, et al.: Global Map of Growth-Regulated Gene Expression in Burkholderia pseudomallei, the Causative Agent of Meloiodosis, Journal of Bacteriology, Dec. 2006, p. 8178-8188.
“Probes of 300 to 1000 bp in length were PCR amplified and spotted in duplicate onto coated glass slides (Full Moon BioSystems, Inc., Sunnyvale, CA).”

Russell S, FlyChip, University of Cambridge, UK, International Drosophila Array Consortium Forum
“We found that 150 mM NaPO[4] with … FMB PowerMatrix slides was best. We prefer PowerMatrix substrates because they are cheaper and more robust.”

Woodard C, Liao G, A Screen for Extracellular Signal-Regulated Kinase-Primed Glycogen Synthase Kinase 3 Substrates Identifies the p53 Inhibitor iASPP, Journal of Virology, 2015 89(18):9232-41 [PubMed]

Yang L, Wang J, Identification of serum biomarkers for gastric cancer diagnosis using a human proteome microarray, Molecular & Cellular Proteomics, 2015 Nov 23. pii: mcp.M115.051250 [PubMed]

Yauk CL, Williams A, et al.: Novel Design and Controls for Focused DNA Microarrays: Applications in Quality Assurance/Control and Normalization for the Health Canada ToxArrayä, BMC Genomics 2006, 7:266.
“Oligonucleotides were … printed unto PowerMatrix slides (Full Moon BioSystems, Sunnyvale, CA, USA) with the ChipWriter Pro robotic arrayer…”

Zheng D, Wan J, Comparison of Humoral Immune Responses to Epstein-Barr Virus and Kaposi’s Sarcoma–Associated Herpesvirus Using a Viral Proteome Microarray, Journal of Infect Dis. (2011) 204 (11): 1683-1691.