The Wnt
signal pathway involves a group of proteins
that are responsible for cell interactions,
proliferation, differentiation, migration
and other functions in animal development.
Studies have found that abnormal Wnt
signaling is related to many human diseases
including cancer and degenerative diseases.
The Wnt
Signaling Phospho Antibody Array
features
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highly specific and well-characterized phosphorylation
antibodies. It allows researchers to
study the important proteins involved in
this pathway. The phospho-specific
antibodies bind to and detect the protein
only when phosphorylated at the specific
site. The non-phospho pairs of the
phospho-specific antibodies are included in
the array to allow comparison based on
phosphorylation state. Each antibody
is printed with six replicates, and the
arrays are printed on standard-size coated
glass microscope slides and can be scanned
on all microarray scanners that are
compatible with 76 x 25 x 1 mm (3 in. x 1
in. x 1mm) slides.
